11^th World Congress on Pediatric Cardiology and Congenital Cardiovascular Disease April 18-19, 2017 London, UK

Track 1: Pediatric Cardiology

 Pediatric cardiology is a branch of medicine dealing with various heart related problems in children, infants, new born. The field incorporates therapeutic conclusion and treatment of innate heart deserts; coronary corridor ailment, heart disappointment, valvular coronary illness and electrophysiology in kids' and the Physicians who have some expertise in this field of solution are called Pediatric cardiologists. This for the most part happened in the youngsters because of Plaque develop thickens and solidifies course dividers, which can repress blood move through your supply routes to your organs and tissues. Atherosclerosis is additionally the most well-known reason for Pediatric cardiovascular sickness. There are a wide range of sorts of heart issues that can influence kids. They incorporate intrinsic heart abandons, viral contaminations that influence the heart, and even coronary illness gained later in youth because of diseases or hereditary disorders.

Related 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13th European Cardiology Conference December 05-06, 2016 Madrid, Spain 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary.

Track 2: Child Interventional Cardiology

Interventional cardiology is truly the future of heart care for children and adults, allowing complex procedures to be successfully completed while leaving the patient with a Band-Aid, rather than a scar. Interventional cardiology is an internally recognized program that provides a full spectrum of diagnostic and interventional cardiac catheterization procedures for the child health. Many children with heart defects can now be treated with interventional or therapeutic cardiac catheterization procedures rather than having to go through heart surgery.

Balloon Valvotomy: An interventional catheterization technique in which an uninflated balloon is placed across a narrowed valve inside the heart. The balloon is inflated while situated across the narrowed valve, increasing the area available for blood flow and decreasing the degree of obstruction. Nearly all balloon valve dilations result in some degree of valve leakiness after the procedure.

Balloon Angioplasty: An invasive catheterization procedure where a narrowed portion of a blood vessel (e.g., coarctation of the aorta, pulmonary artery stenosis) is enlarged by inflating a balloon that straddles the narrowed segment. Severe coarctation of the aorta or pulmonary artery narrowings resemble an hourglass. The balloon dilation intentionally tears part of the wall of the blood vessel.

Stents: Cylindrical metal devices that are placed on a balloon catheter, and are used to enlarge narrowed areas of blood vessels or the airway. When expanded, stents have the appearance of a "chicken wire" cylinder, and resist collapsing. When non-expanded, the stents are long and thin and can be used in blood vessels.

Related 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary; 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA;

Track 3: Pediatric Atherosclerosis

Atherosclerosis begins in childhood with the appearance of aortic fatty streaks. Aortic fatty streaks of some degree are present in practically all individuals from every human population that has been studied. The average amount of aortic intimai surface involved with fatty streaks does not differ much among human populations. Coronary fatty streaks begin to form in adolescence. It is unusual for children or teenagers to have a heart attack or stroke as a result of atherosclerosis. This is because vessel narrowing, caused by atherosclerosis, takes many years to develop. However, the process of atherosclerosis begins in childhood. For most children, atherosclerosis is mild and progresses slowly. In some children, atherosclerosis worsens rapidly, increasing the risk of heart disease, and less commonly, stroke in early adult life. This conversion takes place at earlier ages in populations with high morbidity and mortality from coronary heart disease.

Related 2^nd Annual Conference on Atherosclerosis, Vascular Biology and Thrombosis; 11^th World Congress on Pediatric Cardiology and Congenital Cardiovascular Disease; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; International Conference on Pediatric Neurology November 28-30, 2016 Valencia, Spain USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA;

Track 4: Pediatric Eisenmenger Syndrome

This syndrome may affect adolescents and adults with certain congenital heart defects that were repaired later in life or were never repaired. Though this Pediatric Eisenmenger’s not a type of heart disease specifically, this syndrome typically indicates a problem with the heart. Pediatric Eisenmenger’s is actually a collection of three symptoms, including: cyanosis, pale blue or grayish skin due to decreased oxygen in the blood pulmonary hypertension, high blood pressure in the blood vessels of the lungs polycythaemia, excess number of red blood cells. 

Related 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary; 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA;

Track 5: Adolescent Cardiology

The study of young person who is developing into an adult such adults suffering with heart related problems is studied under adolescent cardiology. Pediatric cardiologists and cardiologists who examine adults frequently receive referrals of adolescents and young adults with chest pain. Chest pain in this age group is most likely non-cardiac in origin, which often creates a diagnostic dilemma for the consultant in terms of the etiology and extent of evaluation are very likely studied in the Adolescent cardiology.

Related 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13th European Cardiology Conference December 05-06, 2016 Madrid, Spain 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary.

Track 6: Pediatric Congenital Heart Disease

An inborn issue otherwise called an innate illness, distortion, birth deformity, or inconsistency, is a condition existing at or before birth paying little heed to bring about. Of these scatters, those portrayed by basic distortions are named "intrinsic peculiarities" and include absconds in a creating baby. Birth surrenders fluctuate generally in cause and side effects. Some intrinsic heart deserts in kids are straightforward and needn't bother with treatment, for example, a little opening between heart chambers that closes all alone. Other intrinsic heart abandons in kids are more intricate and may require a few surgeries performed over a time of quite a long while. The reason for an inborn heart deformity is frequently unknown. Having a guardian with an innate heart imperfection is likewise a danger factor. A number of hereditary conditions are connected with heart absconds including Down disorder, Turner disorder, and Marfan syndrome. Congenital heart imperfections are isolated into two principle bunches:

·         Cyanotic heart abandons

·         Non-cyanotic heart deserts

Related; 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary

Track 7: Pediatric Heart Murmurs

A heart mumble is essentially an additional sound heard when listening to the heart. The ordinary sounds a heart makes are from the valves closing. If there is turbulence, or unsettling influence, in the stream of blood through the heart or real veins around the heart, a mumble might be listened.

Heart mumbles can for the most part be separated into two classifications:

•Murmurs that are not because of basic issues in the heart additionally called "pure mumbles" or "practical mumbles." These mumbles don't for the most part require various line up visits with a cardiologist.

•Murmurs which are because of an auxiliary issue of the heart, (for example, a gap in the heart, a limited heart valve or a defective heart valve). These mumbles require further assessment and catch up with a cardiologist.

Related 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA; International Conference on Angiology; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary

Track 8: Tetralogy of Fallot In Infants

Tetralogy of Fallot is a birth defect that affects normal blood flow through the heart. It happens when a baby’s heart does not form correctly as the baby grows and develops in the mother’s womb during pregnancy. During pregnancy, there are screening tests (also called prenatal tests) to check for birth defects and other conditions. Tetralogy of Fallot might be seen during an ultrasound (which creates pictures of the body). Some findings from the ultrasound may make the health care provider suspect a baby may have tetralogy of Fallot. If so, the health care provider can request a fetal echocardiogram to confirm the diagnosis. A fetal echocardiogram is an ultrasound of the heart of the fetus. This test can show problems with the structure of the heart and how the heart is working with this defect.

Causes and Risk Factors

The causes of heart defects (such as tetralogy of Fallot) among most babies are unknown. Some babies have heart defects because of changes in their genes or chromosomes. Heart defects such as tetralogy of Fallot also are thought to be caused by a combination of genes and other risk factors, such as the things the mother or fetus come in contact with in the environment or what the mother eats or drinks or the medicines she uses.

Related 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13th European Cardiology Conference December 05-06, 2016 Madrid, Spain 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary.

Track 9:   Pediatric Pericarditis

Pericarditis is an irritation or contamination of the pericardium, the slender sac (film) that encompasses the heart. There is a little measure of liquid between the internal and external layers of the pericardium.

In children, pericarditis is well on the way to happen taking after surgery to repair innate (present during childbirth) heart surrenders or obtained coronary illness. In any case, different causes may include:

•           Infection (viral, bacterial, contagious, parasitic)

•           Chest injury or harm

•           Connective tissue issue, for example, systemic lupus erythematosus (lupus)

Diagnosis for pericarditis may include:

·         Blood tests (to evaluate the degree of inflammation)

·         Chest X-ray

·         Echocardiography

Related 14^th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary International Conference on Pediatric Neurology November 28-30, 2016 Valencia, Spain USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA;

Track 10: Adolescent smoking

Smoking among adolescents is an issue that influences nations around the world. It is important to decrease the quantity of young people who begin smoking before this age keeping in mind the end goal to diminish the aggregate number of smokers and damage done to society. Smoking expands the danger of creating cardiovascular sicknesses, which incorporates coronary illness and stroke.

Smoking harms the coating of your supply routes, prompting a development of greasy material (atheroma) which limits the conduit. This can bring about angina, a heart assault or a stroke.The carbon monoxide in tobacco smoke decreases the measure of oxygen in your blood. This implies your heart needs to pump harder to supply the body with the oxygen it needs.

The nicotine in cigarettes fortifies your body to deliver adrenaline, which makes your heart beat quicker and raises your pulse, making your heart work harder.

Your blood will probably cluster, which builds your danger of showing some kindness assault or stroke. Investigate our cardiovascular ailment page to discover more about blood clumps and the harm they can do to your body.

Related 9^th World Dermatology and Pediatric Dermatology Congress October 10-11, 2016 Manchester, UK; Pediatric Cardiology and Congenital Cardiovascular Disease April 17-18, 2017 London, UK.; 10th World Pediatric Congress April 27-28, 2017 Dubai, UAE; 2nd Annual Meeting on Pediatric Nephrology June 29-30,2017 Kuala Lumpur, Malaysia. International Conference on Angiology October 17-18, 2017 Budapest, Hungary International Conference on Pediatric Neurology November 28-30, 2016 Valencia, Spain USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA;

Track 11: Fetal Cardiology

The heart is the primary organ to create in your unborn infant, and is the most imperative to his or her lifetime of wellbeing. Fetal Cardiology program attempts to bolster kid's heart wellbeing, or setting up your tyke forever evolving treatment. The most progressive innovation to screen creating child—including fetal echocardiograms and fetal MRIs for assessment—which decreases hazard while minimizing time spent in the doctor's facility. Our gathering will give you more subtle elements data about fetal cardiovascular physiology, Fetal Bradyarrhythmia's and Tachyarrhythmia's and some more.

·         Fetal Cardiovascular Physiology

·         Irregularities of Venous System

·         Fetal Bradyarrhythmia's

·         Fetal Tachyarrhythmia's

·         Administration of Pregnancy

·         Fetal Cardiac Intervention

·         Transesophageal Echo, Fetal Echo

Related 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary; 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA; International Conference on Angiology; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA.

Track 12: Pediatrics Pulmonary Diagnosis

Specialists are accommodated the conclusion and consideration of unexplained, repetitive and incessant indications or ailments identified with the respiratory  framework for infants, children and adolescents. The vital systems are Bronchoscopy, Impulse Oscillometry, Pulmonary Function Testing and some more.

Following are the diagnosing tests involved in Pediatric Pulmonary Diagnosis are

·         Lung function and structure

·         Lung volume/inflation

·         Lung elasticity and compliance

·         Exercise capability

·         Mouth, throat and tongue functions

·         Allergies

·         Bone density

·         Digestive tract anatomy and function

·         Consequences of recurrent respiratory tract infections

·         Nasal potential difference

·         Laryngoscopy

·         Bronchoscopy

Related 10^th annual World Congress on Pediatrics March 23-25, 2017 (14 Forums, 3 Days, 1 Event) Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary; 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA; International Conference on Angiology; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA

Track 13: Clinical Pediatric Cardiology & Pulmonology

The health related issue which is are included with both lungs and heart amid youth to the youngsters are known as Clinical Pediatric Cardiology and Pulmonology. Research in Cardiology field contains all edges identified with the physiology and pathology of the structure and point of confinement of the heart and the cardiovascular framework, including their control by neuronal and humoral systems, cardiovascular security pharmacology and so on. To see the pharmaceutical impacts on heart, researchers need to do clinical trials on the creatures.

Related 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary; 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA; International Conference on Angiology; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA;

Track 14: Pediatric Cardiovascular Nurses

Heart attendants have an abnormal state of training and experience that permits them to analyze, treat, and oversee conditions that influence the complex cardiovascular framework. They work to advance ideal cardiovascular wellbeing among customers through safeguard measures that include wellbeing guiding, screening, and push tests, and in addition ailment aversion and administration systems. This track having some vital subjects to examine as Obstetrical Nursing, New-conceived Nursing Care, Pediatric Cardiac Nursing, Maternal and Child Health Nursing, Cardiac Intensive Care Nursing, Advanced Nurse Practitioners, Nursing Management and some more.

·         Nursing Management

·         Obstetrical Nursing

·         Infant Nursing Care

·         Maternal and Child Health Nursing

·         Cardiovascular Intensive Care Nursing

·         Pediatric Cardiac Nursing 

Related 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; International Conference on Angiology; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA.

Track 15: Pediatric Cardiac Tumors

Essential cardiovascular tumors are moderately uncommon in the pediatric populace, and they may happen with various signs and indications in fetal or post-natal life. The clinical signs of cardiovascular tumors in fetal life may incorporate arrhythmias, congestive heart disappointment and hydrops. In post-natal life, heart tumors may bring about cyanosis, respiratory trouble, myocardial brokenness, valvular deficiency, arrhythmias, inflow or surge tract deterrents and sudden demise. Surgical treatment is vital when side effects are available, while the part of medicinal treatment can just be palliative. Results are different and identified with the patients' and tumor qualities. Essential considerate heart tumors chiefly have a decent anticipation, while threatening neoplasms more often than not have a poor forecast; in both cases, be that as it may, a strict follow-up is constantly obligatory so as to recognize the repeat of cardiovascular neoplasms after surgery.

Related  3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary.

Track 16: Pediatric Kawasaki Disease

Kawasaki disease is an uncommon youth ailment that influences the blood vessels. The side effects can be extreme for a few days and can look alarming to guardians. In any case, then most youngsters come back to ordinary exercises. Kawasaki illness can hurt the coronary conduits, which convey blood to the heart muscle. Most kids who are dealt with recoup from the sickness without long haul issues. The sickness is most regular in youngsters ages 1 to 2 years and is less basic in kids more seasoned than age 8. It doesn't spread from kid to kid (is not infectious). Infrequently, the malady influences the coronary veins that supply oxygenated blood to the heart. On the off chance that the malady influences the coronary supply routes, it can prompt serious heart issues including myocarditis (irritation of the heart muscle), dysrhythmia (irregular heart musicality), and aneurysm (debilitating and swelling of the course divider).

Related  3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary.

Track 17 : Pediatric Ventricular Septal Defect

The presence of hole, in the heart of new born child, infants is known as Pediatric ventricular septal defect.  In infants with unrestrictive ventricular septal defects will definitely leads to congestive heart failure and that is refractory to medical management and are not growing should undergo surgery to close the defect, regardless of the patients age size. A ventricular septal defect is an abnormal opening in the intervenrticular septum that allows communication between the right and the left ventricular cavity. It is normal for all infants to be born with a small hole between the two atria which usually closes within the first few weeks of life.

Related  3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA. International Conference on Angiology October 17-18, 2017 Budapest, Hungary.

Track 18 :Child Anesthesia For Cardiac Surgery

During the preoperative visit, a member of the Anesthesia team will discuss with the family and patient the use of preoperative medications. The decision regarding whether to administer a preoperative medication will depend on the age of the child, the type of cardiac defect and the anxiety level of the child.

The following are the main drugs mainly used for child

·         Morphine

Morphine is a narcotic that produces sedation and analgesia (blocking the sensation of pain). Morphine may be used as a premedication for certain types of congenital heart defects such as Tetralogy of Fallot or other cyanotic congenital heart diseases.

·         Atropine

 Infants under 6 months of age and children with Down syndrome will sometimes receive a medication called atropine prior to Anesthesia. Atropine is known as an anticholinergic agent, which means it works on the nervous system to produce, among other things, dry mouth and increased heart rate.

·         Midazolam

Midazolam is the drug most commonly given before surgery. In some cases, morphine may also be used. Midazolam (or Versed®) is a short-acting benzodiazepine (sedative) that can be administered to children orally, intranasally or through an intravenous catheter (IV).

Related 3^rd World Summit on Pediatric Cardiology & Pulmonology September 25-27, 2017 Chicago, Illinois, USA Global Summit on Heart Diseases and Therapeutics October 20-21, 2016 Chicago, Illinois, USA; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA; International Conference on Angiology; 13^th European Cardiology Conference December 05-06, 2016 Madrid, Spain; 14th International Conference on Clinical & Experimental Cardiology November 14-16, 2016 Orlando, Florida, USA.